Opioid and propofol pharmacodynamics modeling during brain mapping in awake craniotomy

Ammonia encephalopathy and awake craniotomy for brain language mapping: cause of failed awake craniotomy.

We report the case of an aborted awake craniotomy for a left frontotemporoinsular glioma due to ammonia encephalopathy on a patient taking Levetiracetam, valproic acid and clobazam. This awake mapping surgery was scheduled as a second-stage procedure following partial resection eight days earlier under general anesthesia. We planned to perform the surgery with local anesthesia and sedation with...

Ammonia encephalopathy and awake craniotomy for brain language mapping: Cause of failed awake craniotomy

Awake craniotomy anesthetic management using dexmedetomidine, propofol, and remifentanil

INTRODUCTION Awake craniotomy allows continuous monitoring of patients' neurological functions during open surgery. Anesthesiologists have to sedate patients in a way so that they are compliant throughout the whole surgical procedure, nevertheless maintaining adequate analgesia and anxiolysis. Currently, the use of α2-receptor agonist dexmedetomidine as the primary hypnotic-sedative medication ...

Initial Experience with Brain Mapping under Awake Craniotomy for Resection of Insular Gliomas of the Dominant Hemisphere

Background & Importance: Insular lobe is located at the depth of sylvian fissure and is hidden by frontal, temporal and parietal lobes in close vicinity of internal capsule and basal ganglia and adjacent to the speech centers in the dominant hemisphere. Thus, radical resection of insular gliomas can be even more difficult. Brain mapping techniques can be used to maximize the extent of...

Awake craniotomy

From the Department of Neurosurgery (Bajunaid), Montreal Neurological Institute and Hospital, McGill University, Montreal, Quebec, Canada, the Department of Neurosurgery (Ajlan), Stanford University, Stanford, California, United States of America, the Division of Neurosurgery (Bajunaid), Faculty of Medicine, King Abdulaziz University, Jeddah, and the Division of Neurosurgery (Ajlan), Faculty of...